Originally Posted by
Ace
RetroDuos have ZERO voltage regulation within the console because they ship with a 5V power supply, thus negating the need to put a regulator circuit in the console. It might be possible the NOAC fails due to broken ribbon cables or cold solder joints on either the ribbons or the cartridge slot. I had that happen to me on my FC3 Plus Version 2 where one pin on the cartridge slot had cold solder and I would have to fight with the system for 15 minutes to get it to boot just one NES game. Turned out to be a cold Ground solder joint; reflowed it, works as it did day 1.
NOACs are usually quite durable, I have two FC Game Console Version 1s (60-pin and 72-pin variety, the first legal NOAC-based clones produced back in 2005) that are still going strong after about 12 years. In fact, I have a SuperJoy dating back to 1999 with a rather shit NOAC that still works. The only time I've seen an NOAC fail was when it was overvolted with unregulated DC from a 10V power supply after a resistor was dropped into the system, shorting the capacitors on the DC input with the capacitors on the power pins of the NOAC. Instant death.
In regards to the 3.3V RAM, if your RetroN3 is like my 2.4GHz Edition, four of the five RAM chips will already be 5V RAM, so only one chip will need replacing. Much better than replacing every single RAM chip in a clone that uses ONLY 3.3V RAM, especially those like the Super Retro Trio which use TSOP chips (those are a bitch to work with).